2LVZ

Solution structure of a Eosinophil Cationic Protein-trisaccharide heparin mimetic complex

2LVZ の概要

• エントリーDOI: 10.2210/pdb2lvz/pdb
• NMR情報: BMRB: 18596
• 分子名称: Eosinophil cationic protein, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-propan-2-yl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside (2 entities in total)
• 機能のキーワード: heparin, molecular recognition, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16557.72

構造登録者

Garcia Mayoral, M.,Canales, A.,Diaz, D.,Lopez Prados, J.,Moussaoui, M.,de Paz, J.,Angulo, J.,Nieto, P.,Jimenez Barbero, J.,Boix, E.,Bruix, M. (登録日: 2012-07-17, 公開日: 2013-07-31, 最終更新日: 2020-07-29)

• 主引用文献: Garcia-Mayoral, M.F.,Canales, A.,Diaz, D.,Lopez-Prados, J.,Moussaoui, M.,de Paz, J.L.,Angulo, J.,Nieto, P.M.,Jimenez-Barbero, J.,Boix, E.,Bruix, M.; Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR.; Acs Chem.Biol., 8:144-151, 2013; PubMed: 23025322; DOI: 10.1021/cb300386v

実験手法

SOLUTION NMR