2LVE
RECOMBINANT LEN
Summary for 2LVE
Entry DOI | 10.2210/pdb2lve/pdb |
Descriptor | RLEN (2 entities in total) |
Functional Keywords | immunoglobulin, kappa-iv, light chain dimer |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 12650.01 |
Authors | Schiffer, M.,Pokkuluri, P.R. (deposition date: 1998-05-13, release date: 1999-05-18, Last modification date: 2024-10-09) |
Primary citation | Pokkuluri, P.R.,Huang, D.B.,Raffen, R.,Cai, X.,Johnson, G.,Stevens, P.W.,Stevens, F.J.,Schiffer, M. A domain flip as a result of a single amino-acid substitution. Structure, 6:1067-1073, 1998 Cited by PubMed Abstract: The self-assembly properties of beta domains are important features of diverse classes of proteins that include cell-adhesion molecules, surface receptors and the immunoglobulin superfamily. Immunoglobulin light-chain variable domains are well suited to the study of structural factors that determine dimerization, including how residues at the interface influence the preferred dimer arrangement. PubMed: 9739086DOI: 10.1016/S0969-2126(98)00107-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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