2LVE

RECOMBINANT LEN

2LVE の概要

• エントリーDOI: 10.2210/pdb2lve/pdb
• 分子名称: RLEN (2 entities in total)
• 機能のキーワード: immunoglobulin, kappa-iv, light chain dimer
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12650.01

構造登録者

Schiffer, M.,Pokkuluri, P.R. (登録日: 1998-05-13, 公開日: 1999-05-18, 最終更新日: 2024-10-09)

主引用文献

Pokkuluri, P.R.,Huang, D.B.,Raffen, R.,Cai, X.,Johnson, G.,Stevens, P.W.,Stevens, F.J.,Schiffer, M.
A domain flip as a result of a single amino-acid substitution.
Structure, 6:1067-1073, 1998

PubMed Abstract: The self-assembly properties of beta domains are important features of diverse classes of proteins that include cell-adhesion molecules, surface receptors and the immunoglobulin superfamily. Immunoglobulin light-chain variable domains are well suited to the study of structural factors that determine dimerization, including how residues at the interface influence the preferred dimer arrangement.

PubMed: 9739086
DOI: 10.1016/S0969-2126(98)00107-5

実験手法

X-RAY DIFFRACTION (2.7 Å)