2LT7

Solution NMR structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA

2LT7 の概要

• エントリーDOI: 10.2210/pdb2lt7/pdb
• NMR情報: BMRB: 18462
• 分子名称: Transcriptional regulator Kaiso, DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), ... (4 entities in total)
• 機能のキーワード: zinc finger, double helix, metal binding protein-dna complex, metal binding protein/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q86T24
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 27933.36

構造登録者

Buck-Koehntop, B.A.,Stanfield, R.L.,Ekiert, D.C.,Martinez-Yamout, M.A.,Dyson, H.,Wilson, I.A.,Wright, P.E. (登録日: 2012-05-15, 公開日: 2012-09-05, 最終更新日: 2024-05-01)

• 主引用文献: Buck-Koehntop, B.A.,Stanfield, R.L.,Ekiert, D.C.,Martinez-Yamout, M.A.,Dyson, H.J.,Wilson, I.A.,Wright, P.E.; Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.; Proc.Natl.Acad.Sci.USA, 109:15229-15234, 2012; PubMed: 22949637; DOI: 10.1073/pnas.1213726109

実験手法

SOLUTION NMR