2LRE

The solution structure of the dimeric Acanthaporin

Replaces:  2KUJ

Summary for 2LRE

• Entry DOI: 10.2210/pdb2lre/pdb
• Related: 2LRD
• NMR Information: BMRB: 18358
• Descriptor: Acanthaporin (1 entity in total)
• Functional Keywords: pore-forming toxin, alpha helix, antimicrobial protein
• Biological source: Acanthamoeba culbertsoni
• Total number of polymer chains: 2
• Total formula weight: 12002.46

Authors

Michalek, M.,Soennichsen, F.D.,Wechselberger, R.,Dingley, A.J.,Wienk, H.,Simanski, M.,Herbst, R.,Lorenzen, I.,Marciano-Cabral, F.,Gelhaus, C.,Groetzinger, J.,Leippe, M. (deposition date: 2012-03-28, release date: 2012-05-02, Last modification date: 2023-06-14)

• Primary citation: Michalek, M.,Sonnichsen, F.D.,Wechselberger, R.,Dingley, A.J.,Hung, C.W.,Kopp, A.,Wienk, H.,Simanski, M.,Herbst, R.,Lorenzen, I.,Marciano-Cabral, F.,Gelhaus, C.,Gutsmann, T.,Tholey, A.,Grotzinger, J.,Leippe, M.; Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba.; Nat.Chem.Biol., 9:37-42, 2013; PubMed: 23143413; DOI: 10.1038/nchembio.1116

Experimental method

SOLUTION NMR