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2LPB

Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15

Replaces:  2KO4
Summary for 2LPB
Entry DOI10.2210/pdb2lpb/pdb
NMR InformationBMRB: 18244
DescriptorMediator of RNA polymerase II transcription subunit 15, General control protein GCN4 (2 entities in total)
Functional Keywordsmediator, activator, co-activator, transcription, nucleus, phosphoprotein, transcription regulation, amino acid biosynthesis, dna-binding
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
More
Cellular locationNucleus: P19659 P03069
Total number of polymer chains2
Total formula weight13473.12
Authors
Primary citationBrzovic, P.S.,Heikaus, C.C.,Kisselev, L.,Vernon, R.,Herbig, E.,Pacheco, D.,Warfield, L.,Littlefield, P.,Baker, D.,Klevit, R.E.,Hahn, S.
The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44:942-953, 2011
Cited by
PubMed: 22195967
DOI: 10.1016/j.molcel.2011.11.008
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

數據於2024-03-27公開中

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