2LPB
Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15
Replaces: 2KO4Summary for 2LPB
Entry DOI | 10.2210/pdb2lpb/pdb |
NMR Information | BMRB: 18244 |
Descriptor | Mediator of RNA polymerase II transcription subunit 15, General control protein GCN4 (2 entities in total) |
Functional Keywords | mediator, activator, co-activator, transcription, nucleus, phosphoprotein, transcription regulation, amino acid biosynthesis, dna-binding |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Nucleus: P19659 P03069 |
Total number of polymer chains | 2 |
Total formula weight | 13473.12 |
Authors | Brzovic, P.S.,Heikaus, C.C.,Kisselev, L.,Vernon, R.,Herbig, E.,Pacheco, D.,Warfield, L.,Littlefield, P.,Baker, D.,Klevit, R.E.,Hahn, S. (deposition date: 2012-02-07, release date: 2012-02-22, Last modification date: 2024-05-01) |
Primary citation | Brzovic, P.S.,Heikaus, C.C.,Kisselev, L.,Vernon, R.,Herbig, E.,Pacheco, D.,Warfield, L.,Littlefield, P.,Baker, D.,Klevit, R.E.,Hahn, S. The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. Mol.Cell, 44:942-953, 2011 Cited by PubMed: 22195967DOI: 10.1016/j.molcel.2011.11.008 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report