2LP1
The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99)
Summary for 2LP1
Entry DOI | 10.2210/pdb2lp1/pdb |
NMR Information | BMRB: 15775 |
Descriptor | C99 (1 entity in total) |
Functional Keywords | amyloid precursor protein c-terminal fragment, alzheimer's disease, membrane protein, amyloid-beta precursor, transmembrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 1 |
Total formula weight | 13801.77 |
Authors | Barrett, P.J.,Song, Y.,Van Horn, W.D.,Hustedt, E.J.,Schafer, J.M.,Hadziselimovic, A.,Beel, A.J.,Sanders, C.R. (deposition date: 2012-01-30, release date: 2012-06-06, Last modification date: 2024-05-01) |
Primary citation | Barrett, P.J.,Song, Y.,Van Horn, W.D.,Hustedt, E.J.,Schafer, J.M.,Hadziselimovic, A.,Beel, A.J.,Sanders, C.R. The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Science, 336:1168-1171, 2012 Cited by PubMed: 22654059DOI: 10.1126/science.1219988 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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