2LIX

Solution structure Analysis of the ImKTx104

2LIX の概要

• エントリーDOI: 10.2210/pdb2lix/pdb
• NMR情報: BMRB: 17908
• 分子名称: Potassium Channel Toxins (1 entity in total)
• 機能のキーワード: disulfide bond stabilized structure, toxin
• 由来する生物種: Lychas mucronatus (Chinese swimming scorpion)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2929.46

構造登録者

Zeng, D.Y.,Jiang, L. (登録日: 2011-09-01, 公開日: 2012-07-25, 最終更新日: 2024-10-30)

主引用文献

Chen, Z.Y.,Zeng, D.Y.,Hu, Y.T.,He, Y.W.,Pan, N.,Ding, J.P.,Cao, Z.J.,Liu, M.L.,Li, W.X.,Yi, H.,Jiang, L.,Wu, Y.L.
Structural and functional diversity of acidic scorpion potassium channel toxins.
Plos One, 7:e35154-e35154, 2012

PubMed Abstract: Although the basic scorpion K(+) channel toxins (KTxs) are well-known pharmacological tools and potential drug candidates, characterization the acidic KTxs still has the great significance for their potential selectivity towards different K(+) channel subtypes. Unfortunately, research on the acidic KTxs has been ignored for several years and progressed slowly.

PubMed: 22511981
DOI: 10.1371/journal.pone.0035154

実験手法

SOLUTION NMR