2LIF

Solution Structure of KKGF

2LIF の概要

• エントリーDOI: 10.2210/pdb2lif/pdb
• NMR情報: BMRB: 17891
• 分子名称: Core protein p21 (1 entity in total)
• 機能のキーワード: signal peptide, e1 envelope protein, core protein, transmembrane, membrane protein, viral protein
• 由来する生物種: Hepatitis C virus JFH-1 (HCV)
• 細胞内の位置: Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein (By similarity). Core protein p19: Virion (By similarity). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p7: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (Probable). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): Q99IB8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2881.54

構造登録者

Montserret, R.,Penin, F. (登録日: 2011-08-29, 公開日: 2012-07-11, 最終更新日: 2024-05-15)

• 主引用文献: Oehler, V.,Filipe, A.,Montserret, R.,da Costa, D.,Brown, G.,Penin, F.,McLauchlan, J.; Structural analysis of hepatitis C virus core-e1 signal Peptide and requirements for cleavage of the genotype 3a signal sequence by signal Peptide peptidase.; J.Virol., 86:7818-7828, 2012; PubMed: 22593157; DOI: 10.1128/JVI.00457-12

実験手法

SOLUTION NMR