2LCF

Solution structure of GppNHp-bound H-RasT35S mutant protein

2LCF の概要

• エントリーDOI: 10.2210/pdb2lcf/pdb
• 分子名称: GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: ras, signaling protein, gtp-bound form, conformational states
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19934.21

構造登録者

Araki, M.,Shima, F.,Yoshikawa, Y.,Muraoka, S.,Ijiri, Y.,Nagahara, Y.,Shirono, T.,Kataoka, T.,Tamura, A. (登録日: 2011-04-28, 公開日: 2011-09-28, 最終更新日: 2024-05-01)

• 主引用文献: Araki, M.,Shima, F.,Yoshikawa, Y.,Muraoka, S.,Ijiri, Y.,Nagahara, Y.,Shirono, T.,Kataoka, T.,Tamura, A.; Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.; J.Biol.Chem., 286:39644-39653, 2011; PubMed: 21930707; DOI: 10.1074/jbc.M111.227074

実験手法

SOLUTION NMR