2LB4

DNA / RNA Hybrid containing a central stereo specific Sp borano phosphate linkage

Summary for 2LB4

• Entry DOI: 10.2210/pdb2lb4/pdb
• Related: 2LAR
• Descriptor: DNA_(5'-D(*AP*TP*GP*GP*TP*BGR*CP*TP*C)-3')_, RNA_(5'-R(*GP*AP*GP*CP*AP*CP*CP*AP*U)-3')_ (2 entities in total)
• Functional Keywords: nucleic acid heteroduplex, rnase h1 activity, dna-rna complex, dna/rna
• Total number of polymer chains: 2
• Total formula weight: 5598.42

Authors

Johnson, C.N.,Spring, A.M.,Shaw, B.R.,Germann, M.W. (deposition date: 2011-03-22, release date: 2011-06-29, Last modification date: 2024-05-01)

• Primary citation: Johnson, C.N.,Spring, A.M.,Sergueev, D.,Shaw, B.R.,Germann, M.W.; Structural Basis of the RNase H1 Activity on Stereo Regular Borano Phosphonate DNA/RNA Hybrids.; Biochemistry, 50:3903-3912, 2011; PubMed: 21443203; DOI: 10.1021/bi200083d

Experimental method

SOLUTION NMR