2L3B

Solution NMR structure of the BT_0084 lipoprotein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR376

2L3B の概要

• エントリーDOI: 10.2210/pdb2l3b/pdb
• NMR情報: BMRB: 17176
• 分子名称: Conserved protein found in conjugate transposon (1 entity in total)
• 機能のキーワード: beta, structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, unknown function
• 由来する生物種: Bacteroides thetaiotaomicron
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15183.69

構造登録者

Ramelot, T.A.,Yang, Y.,Wang, D.,Ciccosanti, C.,Janjua, H.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Kennedy, M.A.,Northeast Structural Genomics Consortium (NESG) (登録日: 2010-09-10, 公開日: 2010-11-10, 最終更新日: 2024-05-15)

主引用文献

Ramelot, T.A.,Yang, Y.,Xiao, R.,Acton, T.B.,Everett, J.K.,Montelione, G.T.,Kennedy, M.A.
Solution NMR structure of BT_0084, a conjugative transposon lipoprotein from Bacteroides thetaiotamicron.
Proteins, 80:667-670, 2012

PubMed Abstract: Here we describe the solution NMR structure of the 120 amino acid fragment of BT_0084, without the N-terminal lipoprotein targeting sequence, encoded in a conjugative transposon (CTn) in the genome of Bacteroides thetaiotamicron. BT_0084 belongs to a conserved family of TraQ lipoproteins that are encoded at the end of the tra operon, which contains genes essential for transfer of CTns. The structure belongs to the immunoglobulin superfamily and shares structural similarity, albeit low sequence identity (< 15%), to other proteins involved in pili production for bacterial cell attachment. Although its role in repression of CTn transfer remains to be determined, the structure of BT_0084 reported here represents the first from the Bacteroides TraQ family and should facilitate further understanding of the tra operon-regulated transfer of CTns.

PubMed: 22116783
DOI: 10.1002/prot.23235

実験手法

SOLUTION NMR