2L2A

Mutated Domain 11 of the Cytoplasmic region of the Cation-independent mannose-6-phosphate receptor

2L2A の概要

• エントリーDOI: 10.2210/pdb2l2a/pdb
• 関連するPDBエントリー: 1GP0 2CNJ 2L21 2L29
• 分子名称: Insulin-like growth factor 2 receptor variant (1 entity in total)
• 機能のキーワード: mannose 6 phosphate receptor, protein evolution, insulin-like growth factor 2, genomic imprinting, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15434.52

構造登録者

Williams, C.,Hoppe, H.,Rezgui, D.,Strickland, M.,Frago, S.,Ellis, R.Z.,Wattana-Amorn, P.,Prince, S.N.,Zaccheo, O.J.,Forbes, B.,Jones, E.Y.,Crump, M.P.,Hassan, A.B. (登録日: 2010-08-13, 公開日: 2012-02-15, 最終更新日: 2012-12-12)

• 主引用文献: Williams, C.,Hoppe, H.J.,Rezgui, D.,Strickland, M.,Forbes, B.E.,Grutzner, F.,Frago, S.,Ellis, R.Z.,Wattana-Amorn, P.,Prince, S.N.,Zaccheo, O.J.,Nolan, C.M.,Mungall, A.J.,Jones, E.Y.,Crump, M.P.,Hassan, A.B.; An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.; Science, 338:1209-1213, 2012; PubMed: 23197533; DOI: 10.1126/science.1228633

実験手法

SOLUTION NMR