2L14

Structure of CBP nuclear coactivator binding domain in complex with p53 TAD

2L14 の概要

• エントリーDOI: 10.2210/pdb2l14/pdb
• NMR情報: BMRB: 17073
• 分子名称: CREB-binding protein, Cellular tumor antigen p53 (2 entities in total)
• 機能のキーワード: p53, cbp, p300, tad, protein binding
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P45481; Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 12142.66

構造登録者

Lee, C.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E. (登録日: 2010-07-22, 公開日: 2010-11-03, 最終更新日: 2024-05-01)

• 主引用文献: Lee, C.W.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E.; Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.; Biochemistry, 49:9964-9971, 2010; PubMed: 20961098; DOI: 10.1021/bi1012996

実験手法

SOLUTION NMR