2KV6
Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether
Summary for 2KV6
Entry DOI | 10.2210/pdb2kv6/pdb |
Descriptor | 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide (3 entities in total) |
Functional Keywords | dna-peptide conjugate, trimethylene, acrolein-dg adduct, dna-peptide complex, dna binding protein-dna complex, dna binding protein/dna |
Total number of polymer chains | 3 |
Total formula weight | 7960.63 |
Authors | Huang, H.,Kozekov, I.D.,Kozekova, A.,Rizzo, C.J.,McCullough, A.,LLoyd, R.S.,Stone, M.P. (deposition date: 2010-03-08, release date: 2010-07-21, Last modification date: 2011-07-13) |
Primary citation | Huang, H.,Kozekov, I.D.,Kozekova, A.,Rizzo, C.J.,McCullough, A.K.,Lloyd, R.S.,Stone, M.P. Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage . Biochemistry, 49:6155-6164, 2010 Cited by PubMed: 20604523DOI: 10.1021/bi100364f PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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