2KUO
Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response
Summary for 2KUO
Entry DOI | 10.2210/pdb2kuo/pdb |
NMR Information | BMRB: 16744 |
Descriptor | Aprataxin and PNK-like factor, ZINC ION (2 entities in total) |
Functional Keywords | aprataxin pnk-like factor (aplf), poly adp-ribose (par), par-binding zinc finger (pbz), dna damage, adp-ribose, adp-ribosylation, dna repair, metal-binding, nucleotide-binding, nucleus, zinc, zinc-finger, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q8IW19 |
Total number of polymer chains | 1 |
Total formula weight | 10403.14 |
Authors | Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A. (deposition date: 2010-02-23, release date: 2010-05-05, Last modification date: 2024-05-22) |
Primary citation | Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A. Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
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