2KUO

Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response

2KUO の概要

• エントリーDOI: 10.2210/pdb2kuo/pdb
• NMR情報: BMRB: 16744
• 分子名称: Aprataxin and PNK-like factor, ZINC ION (2 entities in total)
• 機能のキーワード: aprataxin pnk-like factor (aplf), poly adp-ribose (par), par-binding zinc finger (pbz), dna damage, adp-ribose, adp-ribosylation, dna repair, metal-binding, nucleotide-binding, nucleus, zinc, zinc-finger, metal binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q8IW19
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10403.14

構造登録者

Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A. (登録日: 2010-02-23, 公開日: 2010-05-05, 最終更新日: 2022-03-16)

• 主引用文献: Li, G.Y.,McCulloch, R.D.,Fenton, A.,Cheung, M.,Meng, L.,Ikura, M.,Koch, C.A.; Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response; To be Published,

実験手法

SOLUTION NMR