2KRI

Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding module from LDLR determined with Haddock

2KRI の概要

• エントリーDOI: 10.2210/pdb2kri/pdb
• NMR情報: BMRB: 16639
• 分子名称: Beta-2-glycoprotein 1, Low-density lipoprotein receptor, CALCIUM ION (3 entities in total)
• 機能のキーワード: antiphospholipid syndrome, thrombosis, ldlr, receptor, disulfide bond, glycoprotein, heparin-binding, sushi, protein binding-endocytosis complex, protein binding/endocytosis
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14017.92

構造登録者

Beglova, N. (登録日: 2009-12-18, 公開日: 2010-03-31, 最終更新日: 2019-11-06)

• 主引用文献: Lee, C.J.,De Biasio, A.,Beglova, N.; Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids.; Structure, 18:366-376, 2010; PubMed: 20223219; DOI: 10.1016/j.str.2009.12.013

実験手法

SOLUTION NMR