2KQN
Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain
Summary for 2KQN
Entry DOI | 10.2210/pdb2kqn/pdb |
Related | 2KQM |
NMR Information | BMRB: 16607 |
Descriptor | Ig kappa chain V-I region AU (1 entity in total) |
Functional Keywords | amyloidosis, immunoglobulin kappa light chain, homodimer, bence-jones protein, disulfide bond, immunoglobulin domain, immunoglobulin v region, immune system |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 24308.74 |
Authors | Volkman, B.F.,Peterson, F.C.,Ramirez-Alvarado, M.,Baden, E.M. (deposition date: 2009-11-11, release date: 2010-03-16, Last modification date: 2022-03-16) |
Primary citation | Peterson, F.C.,Baden, E.M.,Owen, B.A.,Volkman, B.F.,Ramirez-Alvarado, M. A single mutation promotes amyloidogenicity through a highly promiscuous dimer interface. Structure, 18:563-570, 2010 Cited by PubMed: 20462490DOI: 10.1016/j.str.2010.02.012 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report