2KQG

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics

Replaces:  2KJ0

Summary for 2KQG

• Entry DOI: 10.2210/pdb2kqg/pdb
• Related: 2KQH
• Descriptor: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3', POTASSIUM ION (2 entities in total)
• Functional Keywords: c-kit2, oncogene, promoter, g-quadruplex, dna
• Total number of polymer chains: 1
• Total formula weight: 6713.45

Authors

Hsu, S.-T.D.,Varnai, P.,Bugaut, A.,Reszka, A.P.,Neidle, S.,Balasubramanian, S. (deposition date: 2009-11-05, release date: 2009-11-24, Last modification date: 2011-07-13)

• Primary citation: Hsu, S.-T.D.,Varnai, P.,Bugaut, A.,Reszka, A.P.,Neidle, S.,Balasubramanian, S.; A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics; J.Am.Chem.Soc., 131:13399-13409, 2009; PubMed: 19705869; DOI: 10.1021/ja904007p

Experimental method

SOLUTION NMR