2KQ6

The structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity

2KQ6 の概要

• エントリーDOI: 10.2210/pdb2kq6/pdb
• NMR情報: BMRB: 16590
• 分子名称: Polycystin-2 (1 entity in total)
• 機能のキーワード: protein x, calcium, coiled coil, disease mutation, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, polymorphism, transmembrane, transport, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9009.58

構造登録者

Petri, E.T.,Celic, A.,Kennedy, S.D.,Ehrlich, B.E.,Boggon, T.J.,Hodsdon, M.E. (登録日: 2009-10-28, 公開日: 2010-05-12, 最終更新日: 2024-05-08)

• 主引用文献: Petri, E.T.,Celic, A.,Kennedy, S.D.,Ehrlich, B.E.,Boggon, T.J.,Hodsdon, M.E.; Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity.; Proc.Natl.Acad.Sci.USA, 107:9176-9181, 2010; PubMed: 20439752; DOI: 10.1073/pnas.0912295107

実験手法

SOLUTION NMR