2KO7

Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate

2KO7 の概要

• エントリーDOI: 10.2210/pdb2ko7/pdb
• NMR情報: BMRB: 16491
• 分子名称: Peptidyl-prolyl cis-trans isomerase, ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-dioxopiperidin-1-yl)acetate (2 entities in total)
• 機能のキーワード: cis-trans isomerase, fkbp, cycloheximide-n-ethylethanoate, complex, isomerase, rotamase, structural genomics, ssgcid, seattle structural genomics center for infectious disease
• 由来する生物種: Burkholderia pseudomallei (Pseudomonas pseudomallei)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12607.14

構造登録者

Zheng, S.,Leeper, T.,Varani, G.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2009-09-11, 公開日: 2009-09-29, 最終更新日: 2024-05-01)

• 主引用文献: Norville, I.H.,O'Shea, K.,Sarkar-Tyson, M.,Zheng, S.,Titball, R.W.,Varani, G.,Harmer, N.J.; The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.; Biochem.J., 437:413-422, 2011; PubMed: 21574961; DOI: 10.1042/BJ20110345

実験手法

SOLUTION NMR