2KNY

Fusion construct of CR17 from LRP-1 and ApoE residues 130-149

2KNY の概要

• エントリーDOI: 10.2210/pdb2kny/pdb
• NMR情報: BMRB: 16483
• 分子名称: LRP-1, linker, Apo-E, CALCIUM ION (2 entities in total)
• 機能のキーワード: lrp, apoe, lipoprotein receptor, ligand binding module, complement repeat, calcium, cell membrane, coated pit, cytoplasm, developmental protein, disulfide bond, egf-like domain, endocytosis, glycoprotein, membrane, metal-binding, nucleus, phosphoprotein, polymorphism, receptor, transmembrane, protein binding, metal binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8439.51

構造登録者

Guttman, M.,Komives, E.A. (登録日: 2009-09-08, 公開日: 2010-04-14, 最終更新日: 2020-02-26)

• 主引用文献: Guttman, M.,Prieto, J.H.,Handel, T.M.,Domaille, P.J.,Komives, E.A.; Structure of the minimal interface between ApoE and LRP.; J.Mol.Biol., 398:306-319, 2010; PubMed: 20303980; DOI: 10.1016/j.jmb.2010.03.022

実験手法

SOLUTION NMR