Structure of the trimethylene N2-dG:N2-dG interstrand cross-link in 5'-CpG-3' sequence context

Summary for 2KNK

Related1HZ2 2KNL
DescriptorDNA (5'-D(*AP*GP*GP*CP*GP*CP*CP*T)-3'), PROPANE (2 entities in total)
Functional Keywordsinterstrand cross-link, trimethylene, cpg sequence context, dna
Total number of polymer chains2
Total molecular weight4899.31
Huang, H.,Dooley, P.A.,Harris, C.M.,Harris, T.M.,Stone, M.P. (deposition date: 2009-08-26, release date: 2009-09-29, Last modification date: 2011-07-13)
Primary citation
Huang, H.,Dooley, P.A.,Harris, C.M.,Harris, T.M.,Stone, M.P.
Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.
Chem.Res.Toxicol., 22:1810-1816, 2009
PubMed: 19916525 (PDB entries with the same primary citation)
DOI: 10.1021/tx900225c
MImport into Mendeley
Experimental method

Structure validation

Clashscore0MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures