2KMX

Solution structure of the nucleotide binding domain of the human Menkes protein in the ATP-bound form

2KMX の概要

• エントリーDOI: 10.2210/pdb2kmx/pdb
• 関連するPDBエントリー: 2kmv
• NMR情報: BMRB: 16441
• 分子名称: Copper-transporting ATPase 1, ADENOSINE-5'-TRIPHOSPHATE (2 entities in total)
• 機能のキーワード: atp7a, menkes, atpase, nucleotide binding protein, alternative splicing, atp-binding, cell membrane, copper, copper transport, cytoplasm, disease mutation, endoplasmic reticulum, glycoprotein, golgi apparatus, hydrolase, ion transport, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, polymorphism, transmembrane, transport
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20776.98

構造登録者

Banci, L.,Bertini, I.,Cantini, F.,Inagaki, S.,Migliardi, M.,Rosato, A. (登録日: 2009-08-05, 公開日: 2009-12-01, 最終更新日: 2024-05-01)

• 主引用文献: Banci, L.,Bertini, I.,Cantini, F.,Inagaki, S.,Migliardi, M.,Rosato, A.; The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.; J.Biol.Chem., 2009; PubMed: 19917612; DOI: 10.1074/jbc.M109.054262

実験手法

SOLUTION NMR