2KKG

NMR structure of the octarepeat region of prion protein bound to pentosan polysulfate

2KKG の概要

• エントリーDOI: 10.2210/pdb2kkg/pdb
• NMR情報: BMRB: 16505
• 分子名称: Major prion protein (1 entity in total)
• 機能のキーワード: prion protein, octapeptide repeats, pentosan polysulfate, sulfated glycans, cell membrane, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, prion, membrane protein
• 由来する生物種: Mesocricetus auratus (golden hamsters)
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04273
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8696.39

構造登録者

Taubner, L.M.,Caughey, B.,Copie, V. (登録日: 2009-06-19, 公開日: 2009-11-10, 最終更新日: 2024-05-22)

• 主引用文献: Taubner, L.M.,Bienkiewicz, E.A.,Copie, V.,Caughey, B.; Structure of the flexible amino-terminal domain of prion protein bound to a sulfated glycan.; J.Mol.Biol., 395:475-490, 2010; PubMed: 19913031; DOI: 10.1016/j.jmb.2009.10.075

実験手法

SOLUTION NMR