2KIA

Solution structure of Myosin VI C-terminal cargo-binding domain

2KIA の概要

• エントリーDOI: 10.2210/pdb2kia/pdb
• 分子名称: Myosin-VI (1 entity in total)
• 機能のキーワード: myosin vi, cargo-binding domain, molecular motor, actin-binding, atp-binding, calmodulin-binding, cell projection, coated pit, coiled coil, cytoplasm, cytoplasmic vesicle, deafness, disease mutation, endocytosis, golgi apparatus, hearing, membrane, motor protein, myosin, nucleotide-binding, nucleus, phosphoprotein, protein transport, transport
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q64331
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15385.69

構造登録者

Feng, W.,Yu, C.,Wei, Z.,Miyanoiri, Y.,Zhang, M. (登録日: 2009-04-29, 公開日: 2009-09-29, 最終更新日: 2021-11-10)

• 主引用文献: Yu, C.,Feng, W.,Wei, Z.,Miyanoiri, Y.,Wen, W.,Zhao, Y.,Zhang, M.; Myosin VI undergoes cargo-mediated dimerization; Cell(Cambridge,Mass.), 138:537-548, 2009; PubMed: 19665975; DOI: 10.1016/j.cell.2009.05.030

実験手法

SOLUTION NMR