2KHH
Structural requirements for the UBA domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation Tho complex component Hpr1 and nucleoporin FxFG repeats
Summary for 2KHH
Entry DOI | 10.2210/pdb2khh/pdb |
Descriptor | mRNA export factor MEX67, FxFG (2 entities in total) |
Functional Keywords | mex67, uba, fxfg, mrna export, cytoplasm, leucine-rich repeat, mrna transport, nucleus, transport, transport protein |
Biological source | Saccharomyces cerevisiae (yeast) More |
Cellular location | Nucleus: Q99257 |
Total number of polymer chains | 2 |
Total formula weight | 7754.70 |
Authors | Hobeika, M.,Brockmann, C.,Gruessing, F.,Neuhaus, D.,Divita, G.,Stewart, M.,Dargemont, C. (deposition date: 2009-04-06, release date: 2009-05-12, Last modification date: 2024-05-29) |
Primary citation | Hobeika, M.,Brockmann, C.,Gruessing, F.,Neuhaus, D.,Divita, G.,Stewart, M.,Dargemont, C. Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats J.Biol.Chem., 284:17575-17583, 2009 Cited by PubMed: 19401465DOI: 10.1074/jbc.M109.004374 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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