2KFM

Mouse Prion Protein (121-231) with Mutations Y225A and Y226A

Summary for 2KFM

Related2KFL 2KFO
DescriptorMajor prion protein (1 entity in total)
Functional Keywordsmouse prion protein, mutation y225a, y226a, long-range effect, cell membrane, glycoprotein, golgi apparatus, gpi-anchor, hydroxylation, lipoprotein, membrane, polymorphism, prion, membrane protein, unknown function
Biological sourceMus musculus (mouse)
Cellular locationCell membrane ; Lipid-anchor, GPI-anchor P04925
Total number of polymer chains1
Total molecular weight13224.68
Authors
Christen, B.,Hornemann, S.,Damberger, F.F.,Wuthrich, K. (deposition date: 2009-02-24, release date: 2009-06-16, Last modification date: 2017-11-22)
Primary citation
Christen, B.,Hornemann, S.,Damberger, F.F.,Wuthrich, K.
Prion Protein NMR Structure from Tammar Wallaby (Macropus eugenii) Shows that the beta2-alpha2 Loop Is Modulated by Long-Range Sequence Effects.
J.Mol.Biol., 389:833-845, 2009
PubMed: 19393664 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2009.04.040
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers11.6%12.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2kfm
no rotation
Molmil generated image of 2kfm
rotated about x axis by 90°
Molmil generated image of 2kfm
rotated about y axis by 90°