2KE5

Solution structure and dynamics of the small GTPase Ralb in its active conformation: significance for effector protein binding

2KE5 の概要

• エントリーDOI: 10.2210/pdb2ke5/pdb
• 分子名称: Ras-related protein Ral-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: ral, cancer, signalling, g protein, gtpase, cell membrane, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, signaling protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side: P11234
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20452.97

構造登録者

Fenwick, R.,Prasannan, S.,Campbell, L.J.,Nietlispach, D.,Evetts, K.A.,Camonis, J.,Mott, H.R.,Owen, D. (登録日: 2009-01-23, 公開日: 2009-02-17, 最終更新日: 2024-05-29)

• 主引用文献: Fenwick, R.B.,Prasannan, S.,Campbell, L.J.,Nietlispach, D.,Evetts, K.A.,Camonis, J.,Mott, H.R.,Owen, D.; Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding; Biochemistry, 48:2192-2206, 2009; PubMed: 19166349; DOI: 10.1021/bi802129d

実験手法

SOLUTION NMR