2KBY
The Tetramerization Domain of Human p73
Summary for 2KBY
| Entry DOI | 10.2210/pdb2kby/pdb |
| Descriptor | Tumor protein p73 (1 entity in total) |
| Functional Keywords | tetramerization domain, activator, alternative splicing, anti-oncogene, apoptosis, cell cycle, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, zinc |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus: O15350 |
| Total number of polymer chains | 4 |
| Total formula weight | 24139.31 |
| Authors | Coutandin, D.,Ikeya, T.,Loehr, F.,Guntert, P.,Ou, H.D.,Doetsch, V. (deposition date: 2008-12-12, release date: 2009-09-29, Last modification date: 2022-03-16) |
| Primary citation | Coutandin, D.,Lohr, F.,Niesen, F.H.,Ikeya, T.,Weber, T.A.,Schafer, B.,Zielonka, E.M.,Bullock, A.N.,Yang, A.,Guntert, P.,Knapp, S.,McKeon, F.,Ou, H.D.,Dotsch, V. Conformational stability and activity of p73 require a second helix in the tetramerization domain. Cell Death Differ., 16:1582-1589, 2009 Cited by PubMed: 19763140DOI: 10.1038/cdd.2009.139 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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