2KBS
Solution structure of harmonin PDZ2 in complex with the carboxyl tail peptide of cadherin23
Summary for 2KBS
Entry DOI | 10.2210/pdb2kbs/pdb |
Related | 2KBQ 2KBR |
Descriptor | Harmonin, octameric peptide from Cadherin-23 (2 entities in total) |
Functional Keywords | protein complex, alternative splicing, coiled coil, deafness, hearing, non-syndromic deafness, polymorphism, retinitis pigmentosa, sensory transduction, usher syndrome, vision, calcium, cell adhesion, cell membrane, disease mutation, glycoprotein, membrane, phosphoprotein, transmembrane, structural protein-cell adhesion complex, structural protein/cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): Q9H251 |
Total number of polymer chains | 2 |
Total formula weight | 10593.19 |
Authors | |
Primary citation | Pan, L.,Yan, J.,Wu, L.,Zhang, M. Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 Proc.Natl.Acad.Sci.USA, 106:5575-5580, 2009 Cited by PubMed: 19297620DOI: 10.1073/pnas.0901819106 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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