2KAS

HNE-dG adduct mismatched with dA in basic solution

Summary for 2KAS

• Entry DOI: 10.2210/pdb2kas/pdb
• Related: 2KAR
• Descriptor: 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3', (4S)-nonane-1,4-diol (3 entities in total)
• Functional Keywords: hne-dg, mismatch, hydroxynonenal, dna
• Total number of polymer chains: 2
• Total formula weight: 7511.06

Authors

Huang, H.,Wang, H.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2008-11-13, release date: 2009-05-26, Last modification date: 2022-03-16)

• Primary citation: Huang, H.,Wang, H.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P.; Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA; Chem.Res.Toxicol., 22:187-200, 2009; PubMed: 19053179; DOI: 10.1021/tx800320m

Experimental method

SOLUTION NMR