HNE-dG adduct mismatched with dA in acidic solution

Summary for 2KAR

Descriptor5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3', (4S)-nonane-1,4-diol (3 entities in total)
Functional Keywordshne-dg, mismatch, hydroxynonenal, dna
Total number of polymer chains2
Total molecular weight7511.06
Huang, H.,Wang, H.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2008-11-13, release date: 2009-05-26, Last modification date: 2011-07-13)
Primary citation
Huang, H.,Wang, H.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P.
Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA
Chem.Res.Toxicol., 22:187-200, 2009
PubMed: 19053179 (PDB entries with the same primary citation)
DOI: 10.1021/tx800320m
MImport into Mendeley
Experimental method

Structure validation

Clashscore0MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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