2K72

Solution NMR structure of toxin-like potassium channel blocking domain in MMP23

2K72 の概要

• エントリーDOI: 10.2210/pdb2k72/pdb
• NMR情報: BMRB: 15900
• 分子名称: Matrix metalloproteinase-23 (1 entity in total)
• 機能のキーワード: toxin, metalloprotease, mmp23, potassium channel, cleavage on pair of basic residues, glycoprotein, hydrolase, immunoglobulin domain, membrane, metal-binding, signal-anchor, transmembrane, zinc, zymogen
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4442.34

構造登録者

Khoo, K.K.,Feng, Z.,Norton, R.S. (登録日: 2008-07-31, 公開日: 2010-01-05, 最終更新日: 2023-06-14)

• 主引用文献: Rangaraju, S.,Khoo, K.K.,Feng, Z.P.,Crossley, G.,Nugent, D.,Khaytin, I.,Chi, V.,Pham, C.,Calabresi, P.,Pennington, M.W.,Norton, R.S.,Chandy, K.G.; Potassium channel modulation by a toxin domain in matrix metalloprotease 23.; J.Biol.Chem., 285:9124-9136, 2010; PubMed: 19965868; DOI: 10.1074/jbc.M109.071266

実験手法

SOLUTION NMR