2K60

NMR structure of calcium-loaded STIM1 EF-SAM

2K60 の概要

• エントリーDOI: 10.2210/pdb2k60/pdb
• NMR情報: BMRB: 15851
• 分子名称: PROTEIN (Stromal interaction molecule 1), CALCIUM ION (2 entities in total)
• 機能のキーワード: ef-hand, sam domain, ef-sam, stim1, stromal interaction molecule, store operated calcium entry regulator, soce, endoplasmic reticulum luminal calcium sensor, calcium transport, glycoprotein, ion transport, membrane, phosphoprotein, transmembrane, transport, transport protein, signaling protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: Q13586
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17420.45

構造登録者

Stathopulos, P.B.,Ikura, M. (登録日: 2008-07-02, 公開日: 2008-10-07, 最終更新日: 2013-07-24)

• 主引用文献: Stathopulos, P.B.,Zheng, L.,Li, G.Y.,Plevin, M.J.,Ikura, M.; Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.; Cell(Cambridge,Mass.), 135:110-122, 2008; PubMed: 18854159; DOI: 10.1016/j.cell.2008.08.006

実験手法

SOLUTION NMR