2K4P

Solution Structure of Ship2-Sam

2K4P の概要

• エントリーDOI: 10.2210/pdb2k4p/pdb
• 分子名称: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 (1 entity in total)
• 機能のキーワード: helix bundle, signaling protein, actin-binding, alternative splicing, cell adhesion, cytoplasm, cytoskeleton, diabetes mellitus, hydrolase, immune response, membrane, phosphoprotein, polymorphism, sh2 domain, sh3-binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, cytosol: O15357
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9548.54

構造登録者

Leone, M.,Pellecchia, M. (登録日: 2008-06-16, 公開日: 2008-11-25, 最終更新日: 2022-03-16)

• 主引用文献: Leone, M.,Cellitti, J.,Pellecchia, M.; NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor.; Biochemistry, 47:12721-12728, 2008; PubMed: 18991394; DOI: 10.1021/bi801713f

実験手法

SOLUTION NMR