2K4K

Solution structure of GSP13 from Bacillus subtilis

2K4K の概要

• エントリーDOI: 10.2210/pdb2k4k/pdb
• 分子名称: General stress protein 13 (1 entity in total)
• 機能のキーワード: s1, cytoplasm, stress response, rna binding protein
• 由来する生物種: Bacillus subtilis
• 細胞内の位置: Cytoplasm (Potential): P80870
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14305.22

構造登録者

Yu, W.,Yu, B.,Hu, J.,Jin, C.,Xia, B. (登録日: 2008-06-13, 公開日: 2009-05-12, 最終更新日: 2024-05-29)

主引用文献

Yu, W.,Hu, J.,Yu, B.,Xia, W.,Jin, C.,Xia, B.
Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins.
J.Biomol.Nmr, 43:255-259, 2009

PubMed Abstract: GSP13 encoded by gene yugI is a sigma(B)-dependent general stress protein in Bacillus subtilis, which can be induced by heat shock, salt stress, ethanol stress, glucose starvation, oxidative stress and cold shock. Here we report the solution structure of GSP13 and it is the first structure of S1 domain containing protein in Bacillus subtilis. The structure of GSP13 mainly consists of a typical S1 domain along with a C-terminal 50-residue flexible tail, different from the other known S1 domain containing proteins. Comparison with other S1 domain structures reveals that GSP13 has a conserved RNA binding surface, and it may function similarly to cold shock proteins in response to cold stress.

PubMed: 19152054
DOI: 10.1007/s10858-009-9298-y

実験手法

SOLUTION NMR