2K27

Solution structure of Human Pax8 Paired Box Domain

Summary for 2K27

• Entry DOI: 10.2210/pdb2k27/pdb
• NMR Information: BMRB: 15693
• Descriptor: Paired box protein Pax-8 (1 entity in total)
• Functional Keywords: paired domain, pax8, solution structure, triple frequency, 3d nmr, induced fit, alternative splicing, developmental protein, differentiation, disease mutation, dna-binding, nucleus, paired box, phosphoprotein, polymorphism, transcription, transcription regulation, transcription regulator
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 17447.94

Authors

Codutti, L.,Esposito, G.,Corazza, A.,Fogolari, F.,Tell, G.,Vascotto, C.,van Ingen, H.,Boelens, R.,Viglino, P.,Quadrifoglio, F. (deposition date: 2008-03-26, release date: 2008-09-30, Last modification date: 2023-06-14)

• Primary citation: Codutti, L.,van Ingen, H.,Vascotto, C.,Fogolari, F.,Corazza, A.,Tell, G.,Quadrifoglio, F.,Viglino, P.,Boelens, R.,Esposito, G.; The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family.; J.Biol.Chem., 283:33321-33328, 2008; PubMed: 18829450; DOI: 10.1074/jbc.M805717200

Experimental method

SOLUTION NMR