2K0B

NMR structure of the UBA domain of p62 (SQSTM1)

2K0B の概要

• エントリーDOI: 10.2210/pdb2k0b/pdb
• NMR情報: BMRB: 15591
• 分子名称: Sequestosome-1 (1 entity in total)
• 機能のキーワード: ubiquitin binding, helical bundle, three helices, alternative splicing, apoptosis, cytoplasm, differentiation, disease mutation, endosome, immune response, metal-binding, nucleus, phosphoprotein, polymorphism, zinc, zinc-finger, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q13501
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 5744.41

構造登録者

Long, J.E.,Ciani, B.,Gallagher, T.R.A.,Cavey, J.R.,Sheppard, P.W.,Layfield, R.,Searle, M.S. (登録日: 2008-01-31, 公開日: 2008-02-19, 最終更新日: 2022-03-16)

• 主引用文献: Evans, C.L.,Long, J.E.,Gallagher, T.R.,Hirst, J.D.,Searle, M.S.; Conformation and dynamics of the three-helix bundle UBA domain of p62 from experiment and simulation.; Proteins, 71:227-240, 2007; PubMed: 17932931; DOI: 10.1002/prot.21692

実験手法

SOLUTION NMR