2JYV

Human Granulin F

Summary for 2JYV

Related1QGM 1G26 1FWO 2jyt 2jyu
DescriptorGranulin-2 (1 entity in total)
Functional Keywordsgranulin c, epithelin, human, stack of hairpins, alternative splicing, cytokine, glycoprotein, polymorphism, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted P28799
Total number of polymer chains1
Total molecular weight7978.21
Authors
Tolkatchev, D.,Wang, P.,Chen, Z.,Xu, P.,Ni, F. (deposition date: 2007-12-19, release date: 2008-04-22, Last modification date: 2011-07-13)
Primary citation
Tolkatchev, D.,Malik, S.,Vinogradova, A.,Wang, P.,Chen, Z.,Xu, P.,Bennett, H.P.,Bateman, A.,Ni, F.
Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities.
Protein Sci., 17:711-724, 2008
PubMed: 18359860 (PDB entries with the same primary citation)
DOI: 10.1110/ps.073295308
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers12.3%34.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures