2JYG

Solution Structure of the W184A/M185A Mutant of the Carboxy-terminal Dimerization Domain of the HIV-1 Capsid Protein

2JYG の概要

• エントリーDOI: 10.2210/pdb2jyg/pdb
• 分子名称: Capsid protein p24 (CA) (1 entity in total)
• 機能のキーワード: hiv-1, carboxy-terminal, dimerization domain, ctd, 3d-nmr, capsid protein (ca), double mutant, monomer structure, aids, aspartyl protease, capsid maturation, core protein, cytoplasm, dna integration, dna recombination, dna-directed dna polymerase, endonuclease, hydrolase, lipoprotein, magnesium, membrane, metal-binding, multifunctional enzyme, myristate, nuclease, nucleotidyltransferase, nucleus, phosphoprotein, protease, rna-binding, rna-directed dna polymerase, transferase, viral nucleoprotein, virion, zinc, zinc-finger, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9171.48

構造登録者

Wong, H.C.,Shin, R.,Krishna, N.R. (登録日: 2007-12-13, 公開日: 2008-02-26, 最終更新日: 2021-10-20)

• 主引用文献: Wong, H.C.,Shin, R.,Krishna, N.R.; Solution Structure of a Double Mutant of the Carboxy-Terminal Dimerization Domain of the HIV-1 Capsid Protein.; Biochemistry, 47:2289-2297, 2008; PubMed: 18220423; DOI: 10.1021/bi7022128

実験手法

SOLUTION NMR