2JXB
Structure of CD3epsilon-Nck2 first SH3 domain complex
Summary for 2JXB
Entry DOI | 10.2210/pdb2jxb/pdb |
Descriptor | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 (1 entity in total) |
Functional Keywords | nck, cd3epsilon, t-cell receptor, sh3 domain, immunology, cytoplasm, sh2 domain, signaling protein complex |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P07766 |
Total number of polymer chains | 1 |
Total formula weight | 10267.66 |
Authors | Takeuchi, K.,Yang, H.,Ng, E.,Park, S.,Sun, Z.J.,Reinherz, E.L.,Wagner, G. (deposition date: 2007-11-09, release date: 2008-09-23, Last modification date: 2024-05-29) |
Primary citation | Takeuchi, K.,Yang, H.,Ng, E.,Park, S.Y.,Sun, Z.Y.,Reinherz, E.L.,Wagner, G. Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J.Mol.Biol., 380:704-716, 2008 Cited by PubMed: 18555270DOI: 10.1016/j.jmb.2008.05.037 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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