2JXB

Structure of CD3epsilon-Nck2 first SH3 domain complex

2JXB の概要

• エントリーDOI: 10.2210/pdb2jxb/pdb
• 分子名称: T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 (1 entity in total)
• 機能のキーワード: nck, cd3epsilon, t-cell receptor, sh3 domain, immunology, cytoplasm, sh2 domain, signaling protein complex
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P07766
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10267.66

構造登録者

Takeuchi, K.,Yang, H.,Ng, E.,Park, S.,Sun, Z.J.,Reinherz, E.L.,Wagner, G. (登録日: 2007-11-09, 公開日: 2008-09-23, 最終更新日: 2024-05-29)

• 主引用文献: Takeuchi, K.,Yang, H.,Ng, E.,Park, S.Y.,Sun, Z.Y.,Reinherz, E.L.,Wagner, G.; Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.; J.Mol.Biol., 380:704-716, 2008; PubMed: 18555270; DOI: 10.1016/j.jmb.2008.05.037

実験手法

SOLUTION NMR