2JUN

Structure of the MID1 tandem B-boxes reveals an interaction reminiscent of intermolecular RING heterodimers

2JUN の概要

• エントリーDOI: 10.2210/pdb2jun/pdb
• 分子名称: Midline-1, ZINC ION (2 entities in total)
• 機能のキーワード: midline 1, b-box, trim, ring finger, alternative splicing, coiled coil, cytoplasm, cytoskeleton, disease mutation, ligase, metal-binding, microtubule, phosphorylation, ubl conjugation pathway, zinc, zinc-finger
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: O15344
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11678.75

構造登録者

Tao, H.,Singireddy, S.,Jakkidi, M.,Simmons, B.N.,Short, K.M.,Cox, T.C.,Massiah, M.A. (登録日: 2007-08-31, 公開日: 2008-03-04, 最終更新日: 2024-05-29)

• 主引用文献: Tao, H.,Simmons, B.N.,Singireddy, S.,Jakkidi, M.,Short, K.M.,Cox, T.C.,Massiah, M.A.; Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers; Biochemistry, 47:2450-2457, 2008; PubMed: 18220417; DOI: 10.1021/bi7018496

実験手法

SOLUTION NMR