2JLC

Crystal structure of E.coli MenD, 2-succinyl-5-enolpyruvyl-6-hydroxy- 3-cyclohexadiene-1-carboxylate synthase - native protein

Summary for 2JLC

• Entry DOI: 10.2210/pdb2jlc/pdb
• Related: 2JLA
• Descriptor: 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE, THIAMINE DIPHOSPHATE, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: menaquinone biosynthesis, manganese, transferase, thiamine diphosphate cofactor, thiamine pyrophosphate
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 2
• Total formula weight: 128653.20

Authors

Dawson, A.,Fyfe, P.K.,Hunter, W.N. (deposition date: 2008-09-08, release date: 2008-10-21, Last modification date: 2023-12-13)

• Primary citation: Dawson, A.,Fyfe, P.K.,Hunter, W.N.; Specificity and Reactivity in Menaquinone Biosynthesis: The Structure of Escherichia Coli Mend (2-Succinyl-5-Enolpyruvyl-6-Hydroxy-3-Cyclohexadiene-1-Carboxylate Synthase).; J.Mol.Biol., 384:1353-, 2008; PubMed: 18983854; DOI: 10.1016/J.JMB.2008.10.048

Experimental method

X-RAY DIFFRACTION (2.5 Å)