2JJY

Crystal structure of Francisella tularensis enoyl reductase (ftFabI) with bound NAD

Summary for 2JJY

Entry DOI	10.2210/pdb2jjy/pdb
Descriptor	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total)
Functional Keywords	oxidoreductase, fatty acid biosynthesis
Biological source	FRANCISELLA TULARENSIS
Total number of polymer chains	4
Total formula weight	116288.82
Authors	Luckner, S.R.,Lu, H.,Truglio, J.J.,Tonge, P.J.,Kisker, C. (deposition date: 2008-04-25, release date: 2009-02-24, Last modification date: 2024-05-08)
Primary citation	Lu, H.,England, K.,Am Ende, C.,Truglio, J.J.,Luckner, S.R.,Marlenee, N.,Knudson, S.E.,Knudson, D.L.,Bowen, R.A.,Kisker, C.,Slayden, R.A.,Tonge, P.J. Slow-Onset Inhibition of the Fabi Enoyl Reductase from Francisella Tularensis: Residence Time and in Vivo Activity Acs Chem.Biol., 4:221-, 2009 Cited by PubMed: 19206187 DOI: 10.1021/CB800306Y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation