2JHL

Structure of globular heads of M-ficolin complexed with sialic acid

2JHL の概要

• エントリーDOI: 10.2210/pdb2jhl/pdb
• 関連するPDBエントリー: 2JHH 2JHI 2JHK 2JHM
• 分子名称: FICOLIN-1, CALCIUM ION, N-acetyl-beta-neuraminic acid, ... (4 entities in total)
• 機能のキーワード: lectin, collagen, acidic ph, complement, glycoprotein, polymorphism, innate immunity, sugar-binding protein, sugar binding protein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24725.27

構造登録者

Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C. (登録日: 2007-02-22, 公開日: 2007-10-09, 最終更新日: 2020-07-29)

• 主引用文献: Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Fujita, T.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C.; Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.; J.Biol.Chem., 282:35814-, 2007; PubMed: 17897951; DOI: 10.1074/JBC.M705741200

実験手法

X-RAY DIFFRACTION (1.75 Å)