2JHH

Structure of globular heads of M-ficolin at acidic pH

2JHH の概要

• エントリーDOI: 10.2210/pdb2jhh/pdb
• 関連するPDBエントリー: 2JHI 2JHK 2JHL 2JHM
• 分子名称: FICOLIN-1, CALCIUM ION (3 entities in total)
• 機能のキーワード: lectin, collagen, acidic ph, complement, sugar-binding protein, glycoprotein, polymorphism, innate immunity, sugar binding protein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48832.00

構造登録者

Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C. (登録日: 2007-02-22, 公開日: 2007-10-09, 最終更新日: 2019-04-03)

• 主引用文献: Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Fujita, T.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C.; Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.; J. Biol. Chem., 282:35814-35820, 2007; PubMed: 17897951; DOI: 10.1074/jbc.M705741200

実験手法

X-RAY DIFFRACTION (1.7 Å)